Risk factors of preterm infants with CPAP intubated for mechanical ventilation

Early use of continuous positive airway pressure (CPAP) is equal to the prophylactic administration a surfactant prevent neonatal respiratory distress syndrome (nRDS) in high-risk infants. However, almost half smallest infants still require intubation and mechanical ventilation first 72 hours after birth. It known that ineffective initial CPAP associated with poorer prognosis. Therefore, search for reliable prognostic risk factors very preterm neonates whose support started relevant today. The results retrospective cohort study conducted at Lviv Regional Clinical Hospital (Ukraine), which included 151 children birth weight <1500 g gestational age <32 weeks, showed failure occurred median five 31% initially treated average (SD) FiO2, while point was 0.48 (0.15). prevalence main severe nRDS did not differ significantly between two groups (CPAP success failure). treatment (OR – 7.46; 95% CI: 2.3–24.2), RDS 12.17; 3.8–39.3), requirement resuscitation 3.10; 1.2–8.1), 0.38; 0.15–0.99). Earlier exogenous high developing could need ventilation. Keywords: failure, ventilation, infants,